Medical Device Packaging Validation India | ASTM F88 | NABL

Auriga Research provides NABL-accredited medical device packaging validation per ISO 11607, ASTM F88, and ASTM D4169. Our testing laboratory evaluates sterile barrier system performance, seal integrity, and package durability to support CDSCO registration, FDA 510(k) submissions, and CE marking documentation for sterile medical devices.

Packaging is the last line of defence for sterile devices. Our validation programme covers seal strength, burst testing, dye penetration, microbial barrier properties, accelerated and real-time ageing, and distribution simulation — ensuring your sterile barrier system maintains integrity through manufacturing, transit, storage, and point-of-use opening.

Packaging Testing Scope

  • Seal strength — peel testing per ASTM F88
  • Burst testing — unrestrained (ASTM F1140) and restrained (ASTM F2054)
  • Dye penetration — seal integrity per ASTM F1929
  • Visual seal inspection per ASTM F1886
  • Package integrity — bubble emission (ASTM F2096)
  • Accelerated ageing per ASTM F1980 (Q10 method)
  • Real-time ageing — concurrent shelf life validation
  • Distribution simulation per ASTM D4169 / ISTA 2A/3A
  • Microbial barrier testing per ISO 11607-1 Annex B
  • Tyvek and film tensile strength and elongation

Who Needs Packaging Validation

  • Sterile medical device manufacturers validating new packaging designs
  • Companies changing packaging materials, seal parameters, or sterilisation methods
  • CDSCO, FDA, or CE submissions requiring shelf life validation data
  • Contract packagers establishing process qualification (IQ/OQ/PQ)
  • Quality teams conducting annual packaging revalidation

Turnaround Time

Seal strength, burst testing, and dye penetration take 5-7 business days. Distribution simulation takes 10-15 business days. Accelerated ageing duration depends on the shelf life claim (38 days for 1-year, 114 days for 3-year equivalence at 55 degrees Celsius). Final reports are issued within 5 business days of test completion.

Frequently Asked Questions

What packaging tests are required for sterile medical devices?
Sterile medical device packaging must be validated per ISO 11607-1 (requirements) and ISO 11607-2 (validation processes). Key tests include seal strength per ASTM F88, burst testing per ASTM F1140/F2054, dye penetration per ASTM F1929, visual seal inspection, microbial barrier testing, accelerated ageing per ASTM F1980, and distribution simulation per ASTM D4169 or ISTA protocols. CDSCO and FDA require packaging validation data as part of the device submission dossier.
What is the difference between seal strength and burst testing?
Seal strength testing (ASTM F88) measures the force required to peel open a sealed pouch — it evaluates the consistency and adequacy of the heat seal. Burst testing (ASTM F1140 for unrestrained burst, ASTM F2054 for restrained burst) pressurises the package internally until failure, testing the overall package integrity. Both tests are complementary: seal strength verifies sealing process control, while burst testing detects gross leaks and weak points across the entire package.
How long does accelerated ageing testing take for packaging validation?
Accelerated ageing per ASTM F1980 uses elevated temperature to simulate real-time shelf life. A 1-year shelf life claim requires approximately 38 days at 55 degrees Celsius (using Q10 = 2 and ambient of 23 degrees Celsius). A 3-year shelf life claim requires approximately 114 days. Testing includes seal strength, sterile barrier integrity, and visual inspection at the end of the accelerated ageing period. Real-time ageing must run concurrently to confirm the accelerated results.

Get Your Packaging Validation Quote

NABL-accredited packaging validation per ASTM F88 and ISO 11607. Seal strength, ageing, and distribution testing.

Call Now Get a Quote

Type to search services, tests, and locations…